sparse_primary_supporting_bucket
Central evidence is high but primary supporting bucket is empty. Classification tiers may still be too coarse.
fulltoplow inflation risk
Veillonella
ulcerative colitis
Veillonella looks like a credible signal in ulcerative colitis, though some caution is still warranted.
Veillonella shows a strong literature footprint in ulcerative colitis, with substantial central evidence and broader supporting literature.
veillonella
Credibility score
72
Human translation
4/5
Reproducibility
5/5
Novelty
2/5
Actionability
5/5
Credibility 72Human translation 4/5Reproducibility 5/5Novelty 2/5Actionability 5/5
Why this scores the way it does
- strong central evidence base
- substantial preclinical support
Main caveats
- directionality and confounding still require curated review
Internal review flags
1 flagsPrimary central evidence
26 papersThe gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls.
2017Gut
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease.
2016Genome medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis.
2017World journal of gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A disease-specific decline of the relative abundance of Bifidobacterium in patients with autoimmune hepatitis.
2020Alimentary pharmacology & therapeutics
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Effectiveness of Multi-Session FMT Treatment in Active Ulcerative Colitis Patients: A Pilot Study.
2020Biomedicines
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiome of Children and Adolescents With Primary Sclerosing Cholangitis in Association With Ulcerative Colitis.
2020Frontiers in immunology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A case-control study on the association of intestinal flora with ulcerative colitis.
2021AMB Express
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Intestinal flora differences between patients with ulcerative colitis of different ethnic groups in China.
2021Medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma.
2021Vavilovskii zhurnal genetiki i selektsii
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Patients With Inflammatory Bowel Disease Show IgG Immune Responses Towards Specific Intestinal Bacterial Genera.
2022Frontiers in immunology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Impact of gut Microbiome alteration in Ulcerative Colitis patients on disease severity and outcome.
2023Clinical and experimental medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
2023International microbiology : the official journal of the Spanish Society for Microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota Signatures Are Associated With Psychopathological Profiles in Patients With Ulcerative Colitis: Results From an Italian Tertiary IBD Center.
2023Inflammatory bowel diseases
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population.
2023BMC gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Pro-Inflammatory Diet Is Correlated with High Veillonella rogosae, Gut Inflammation and Clinical Relapse of Inflammatory Bowel Disease.
2023Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Serial Fecal Microbiota Infusions via Colonoscopy for Active Ulcerative Colitis: A Feasibility, Safety, and Translational Monocentric Italian Study.
2023Microorganisms
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Exclusive Enteral Nutrition Mediates Beneficial Gut Microbiome Enrichment in Acute Severe Colitis.
2024Inflammatory bowel diseases
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiosis and Associated Stool Features Improve Prediction of Response to Biological Therapy in Inflammatory Bowel Disease.
2024Gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.
2024Cell host & microbe
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
An integrative multi-omic analysis defines gut microbiota, mycobiota, and metabolic fingerprints in ulcerative colitis patients.
2024Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A Novel Microbial Dysbiosis Index and Intestinal Microbiota-Associated Markers as Tools of Precision Medicine in Inflammatory Bowel Disease Paediatric Patients.
2024International journal of molecular sciences
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Characterization of the gut phageome of Japanese patients with ulcerative colitis under endoscopic remission.
2025Journal of clinical biochemistry and nutrition
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Characterization of the salivary microbiome of adults with inflammatory bowel disease.
2025Journal of oral microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[1]The human gut microbiota in IBD, characterizing hubs, the core microbiota and terminal nodes: a network-based approach.
2025BMC microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis.
2025Nature communications
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal Microbiota Transplantation Induces Sustained Gut Microbiome Changes in Pediatric Ulcerative Colitis: A Combined Randomized and Open-Label Study.
2025Gastro hep advances
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Preclinical supporting evidence
10 papersIntestinal mucosa-associated microflora in ulcerative colitis patients before and after restorative proctocolectomy with an ileoanal pouch.
2008Diseases of the colon and rectum
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokines and gut microbiota modulation.
2020Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Mucosal microbiota and gene expression are associated with long-term remission after discontinuation of adalimumab in ulcerative colitis.
2020Scientific reports
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Impact of Lycium barbarum arabinogalactan on the fecal metabolome in a DSS-induced chronic colitis mouse model.
2022Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
The oral-gut axis: Salivary and fecal microbiome dysbiosis in patients with inflammatory bowel disease.
2022Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients.
2023Journal of clinical biochemistry and nutrition
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Puerarin alleviates inflammation and pathological damage in colitis mice by regulating metabolism and gut microbiota.
2023Frontiers in microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Cooperative interactions between Veillonella ratti and Lactobacillus acidophilus ameliorate DSS-induced ulcerative colitis in mice.
2023Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Anti-inflammatory Effects of Bacteroidota Strains Derived From Outstanding Donors of Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis.
2024Inflammatory bowel diseases
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease.
2024Microbiome
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
4 papersDifferences in Gut Microbiota in Patients With vs Without Inflammatory Bowel Diseases: A Systematic Review.
2020Gastroenterology
Relevant review or meta-analysis for the signal-disease area.
Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecular mechanisms.
2025Critical reviews in microbiology
Relevant review or meta-analysis for the signal-disease area.
A study on the causal relationship between the gut microbiome and herpes zoster using Mendelian randomization.
2024Frontiers in medicine
Relevant review or meta-analysis for the signal-disease area.
Follicular Skin Disorders, Inflammatory Bowel Disease, and the Microbiome: A Systematic Review.
2024International journal of molecular sciences
Relevant review or meta-analysis for the signal-disease area.