Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota.
2016Genome medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
fulltoplow inflation risk
Veillonella
type 2 diabetes
Veillonella is an interesting but still moderate-confidence signal in type 2 diabetes.
Veillonella shows a strong literature footprint in type 2 diabetes, with substantial central evidence and broader supporting literature.
veillonella
Credibility score
52
Human translation
3/5
Reproducibility
4/5
Novelty
3/5
Actionability
4/5
Credibility 52Human translation 3/5Reproducibility 4/5Novelty 3/5Actionability 4/5
Why this scores the way it does
- strong central evidence base
- meaningful supporting human literature
- substantial preclinical support
Main caveats
- directionality and confounding still require curated review
Primary central evidence
16 papersGestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
2018Microbiome
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Identifying Group-Specific Sequences for Microbial Communities Using Long k-mer Sequence Signatures.
2018Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Metabolic improvement in obese patients after duodenal-jejunal exclusion is associated with intestinal microbiota composition changes.
2019International journal of obesity (2005)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Fecal Microbiota Is Already Altered in Normoglycemic Individuals Who Go on to Have Type 2 Diabetes.
2021Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota Composition and Fecal Metabolic Profiling in Patients With Diabetic Retinopathy.
2021Frontiers in cell and developmental biology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Characteristics and Clinical Significance of Intestinal Microbiota in Patients with Chronic Hepatitis B Cirrhosis and Type 2 Diabetes Mellitus.
2022Journal of diabetes research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Alterations in the Gut Microbiota in Pregnant Women with Pregestational Type 2 Diabetes Mellitus.
2023mSystems
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiosis signatures of gut microbiota and the progression of type 2 diabetes: a machine learning approach in a Mexican cohort.
2023Frontiers in endocrinology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Role of Presurgical Gut Microbial Diversity in Roux-en-Y Gastric Bypass Weight-Loss Response: A Cohort Study.
2024Lifestyle genomics
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of germinated brown rice and germinated black rice on people with type 2 diabetes mellitus combined with dyslipidaemia.
2024Food & function
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Integrated Analysis of Oral Microbiome and Metabolome in T2DM Patients With Varying Glycemic Status.
2025Oral diseases
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Sex-Specific Aging Patterns of Gut Microbiota in Urban Chinese Adults: Guild-Based Analysis and Implications for Healthy Aging.
2025Aging cell
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Diabetes alters the supragingival microbiome through plasma-to-saliva migration of glucose and fructose.
2025Microbiome
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Hidden Threat: Maxillary Hardware-Associated Actinomycosis in Diabetes.
2025Cureus
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota Diversity and Function in Adults With Type 2 Diabetes, Alzheimer's Disease, and Both Conditions.
2026International journal of microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Supporting primary evidence
2 papersThe diversity of gut microbiota in type 2 diabetes with or without cognitive impairment.
2021Aging clinical and experimental research
Human primary paper with plausible association relevance to the disease context.
Akkermansia muciniphila is Negatively Correlated with Hemoglobin A1c in Refractory Diabetes.
2020Microorganisms
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
12 papersSubgingival biodiversity in subjects with uncontrolled type-2 diabetes and chronic periodontitis.
2013Journal of periodontal research
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Next generation sequencing of oral microbiota in Type 2 diabetes mellitus prior to and after neem stick usage and correlation with serum monocyte chemoattractant-1.
2017Diabetes research and clinical practice
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Integrative Analysis Toward Different Glucose Tolerance-Related Gut Microbiota and Diet.
2019Frontiers in endocrinology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Effect of heat-killed Streptococcus thermophilus on type 2 diabetes rats.
2019PeerJ
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Duodenal microbiome in patients with or without Helicobacter pylori infection.
2020Helicobacter
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Periodontitis in elderly patients with type 2 diabetes mellitus: impact on gut microbiota and systemic inflammation.
2020Aging
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut microbiota of patients with type 2 diabetes and gastrointestinal intolerance to metformin differs in composition and functionality from tolerant patients.
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.
2023Frontiers in endocrinology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Alterations in subgingival microbiome and advanced glycation end-products levels in periodontitis with and without type 1 diabetes mellitus: a cross-sectional study.
2024BMC oral health
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Artesunate ameliorates diabetic xerostomia in rats through regulating oral microbiota and metabolic profile in salivary gland based on NF-κB/NLRP3 signaling pathway.
2025Phytomedicine : international journal of phytotherapy and phytopharmacology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Potential short-term shift in oral microbiota of patients with stage III-IV periodontitis and type 2 diabetes treated by non-surgical periodontal therapy.
2025Journal of dental sciences
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut dysbiosis, low-grade inflammation, and renal impairment severity in elderly diabetic nephropathy.
2025World journal of diabetes
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
4 papersInorganic nitrate: A potential prebiotic for oral microbiota dysbiosis associated with type 2 diabetes.
2021Nitric oxide : biology and chemistry
Relevant review or meta-analysis for the signal-disease area.
Gut Microbiota Composition in Prediabetes and Newly Diagnosed Type 2 Diabetes: A Systematic Review of Observational Studies.
2022Frontiers in cellular and infection microbiology
Relevant review or meta-analysis for the signal-disease area.
Gut microbiota alterations and their role in the pathophysiology of obesity following bariatric surgery.
2025Expert review of endocrinology & metabolism
Relevant review or meta-analysis for the signal-disease area.
Systematic Review on the Importance of Gut Microbiota in the Regulation of Type 2 Diabetes Through Physical Activity and Exercise.
2025Current issues in molecular biology
Relevant review or meta-analysis for the signal-disease area.