sparse_primary_supporting_bucket
Central evidence is high but primary supporting bucket is empty. Classification tiers may still be too coarse.
fulltoplow inflation risk
Veillonella
inflammatory bowel disease
Veillonella appears to be a strong and relatively human-grounded signal in inflammatory bowel disease.
Veillonella shows a strong literature footprint in inflammatory bowel disease, with substantial central evidence and broader supporting literature.
veillonella
Credibility score
75
Human translation
4/5
Reproducibility
5/5
Novelty
2/5
Actionability
3/5
Credibility 75Human translation 4/5Reproducibility 5/5Novelty 2/5Actionability 3/5
Why this scores the way it does
- strong central evidence base
Main caveats
- directionality and confounding still require curated review
Internal review flags
1 flagsPrimary central evidence
27 papersDysbiosis of salivary microbiota in inflammatory bowel disease and its association with oral immunological biomarkers.
2014DNA research : an international journal for rapid publication of reports on genes and genomes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease.
2016Genome medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.
2017Lancet (London, England)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut mucosal-associated microbiota better discloses inflammatory bowel disease differential patterns than faecal microbiota.
2019Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease - associations with disease phenotype, treatment, and outcome.
2019Clinical and experimental gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Composition and Metabolic Potential of the Human Small Intestinal Microbiota Within the Context of Inflammatory Bowel Disease.
2021Journal of Crohn's & colitis
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal microbiota in congenital chloride diarrhea and inflammatory bowel disease.
2022PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Patients With Inflammatory Bowel Disease Show IgG Immune Responses Towards Specific Intestinal Bacterial Genera.
2022Frontiers in immunology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.
2023International microbiology : the official journal of the Spanish Society for Microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Composition of the gut microbiota in patients with inflammatory bowel disease in Saudi Arabia: A pilot study.
2023Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population.
2023BMC gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Pro-Inflammatory Diet Is Correlated with High Veillonella rogosae, Gut Inflammation and Clinical Relapse of Inflammatory Bowel Disease.
2023Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Deciphering salivary microbiome signature in Crohn's disease patients with different factors contributing to dysbiosis.
2023Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiosis and Associated Stool Features Improve Prediction of Response to Biological Therapy in Inflammatory Bowel Disease.
2024Gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Detecting and quantifying Veillonella by real-time quantitative PCR and droplet digital PCR.
2024Applied microbiology and biotechnology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Inflammatory bowel disease associated with primary sclerosing cholangitis is associated with an altered gut microbiome and bile acid profile.
2024Journal of Crohn's & colitis
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise.
2024Journal of exercise science and fitness
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A Novel Microbial Dysbiosis Index and Intestinal Microbiota-Associated Markers as Tools of Precision Medicine in Inflammatory Bowel Disease Paediatric Patients.
2024International journal of molecular sciences
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Open Label Vancomycin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Improved Colonic Disease Activity and Associations With Changes in Host-Microbiome-Metabolomic Signatures.
2025Journal of Crohn's & colitis
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota in Different Treatment Response Types of Crohn's Disease Patients Treated with Biologics over a Long Disease Course.
2025Biomedicines
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Characterization of the salivary microbiome of adults with inflammatory bowel disease.
2025Journal of oral microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[1]The human gut microbiota in IBD, characterizing hubs, the core microbiota and terminal nodes: a network-based approach.
2025BMC microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Multi-omics integration reveals functional signatures of gut microbiome in atherosclerosis.
2025Gut microbes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
First insights into microbial changes within an Inflammatory Bowel Disease Family Cohort study.
2025Gut microbes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Decoding IBD progression: a dynamic biomarker atlas for personalized disease stratification.
2025Journal of translational medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Genetic architecture of primary sclerosing cholangitis: shared pathways with inflammatory bowel disease and gut-liver axis mediation.
2026International journal of surgery (London, England)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal microbial and metabolic signatures in children with very early onset inflammatory bowel disease.
2025NPJ biofilms and microbiomes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Preclinical supporting evidence
9 papersNLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease.
2018Frontiers in immunology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
The oral-gut axis: Salivary and fecal microbiome dysbiosis in patients with inflammatory bowel disease.
2022Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
SAELGMDA: Identifying human microbe-disease associations based on sparse autoencoder and LightGBM.
2023Frontiers in microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Regulation of gut microbiota and alleviation of DSS-induced colitis by vitexin.
2023European journal of nutrition
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Isolation, identification, and significance of salivary Veillonella spp., Prevotella spp., and Prevotella salivae in patients with inflammatory bowel disease.
2023Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease.
2024Microbiome
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut microbial and metabolomics profiles reveal the potential mechanism of fecal microbiota transplantation in modulating the progression of colitis-associated colorectal cancer in mice.
2024Journal of translational medicine
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis.
2025The Journal of experimental medicine
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut Microbes Secretions May Trigger Mononuclear Cell Migration and Offer Comorbidity Mechanism Between Inflammatory Bowel Disease and Diabetic Retinopathy.
2025Mediators of inflammation
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
5 papersGut microbiome in primary sclerosing cholangitis: A review.
2020World journal of gastroenterology
Relevant review or meta-analysis for the signal-disease area.
Follicular Skin Disorders, Inflammatory Bowel Disease, and the Microbiome: A Systematic Review.
2024International journal of molecular sciences
Relevant review or meta-analysis for the signal-disease area.
Dysbiosis of Gut Microbiota in Microscopic Colitis: Diagnostic and Therapeutic Implications.
2025Diagnostics (Basel, Switzerland)
Relevant review or meta-analysis for the signal-disease area.
Anaerobic gut bacteria and their potential role in the initiation, exacerbation, and development of human colorectal cancer: a narrative review.
2025Frontiers in cellular and infection microbiology
Relevant review or meta-analysis for the signal-disease area.
Gut microbiome remodeling induced by microplastic exposure in humans.
2026Gut microbes
Relevant review or meta-analysis for the signal-disease area.