preclinical_heavy
Preclinical evidence exceeds central human evidence. Interpret translational relevance cautiously.
candidateweakhigh inflation risk
Micrococcus
atopic dermatitis
Micrococcus has meaningful literature visibility in atopic dermatitis, but the current evidence mix suggests a substantial risk of overclaiming.
Micrococcus has a broader but less central evidence footprint in atopic dermatitis, with support coming from indirect, review, or preclinical literature.
micrococcus
Credibility score
12
Human translation
2/5
Reproducibility
2/5
Novelty
5/5
Actionability
1/5
Credibility 12Human translation 2/5Reproducibility 2/5Novelty 5/5Actionability 1/5
Why this scores the way it does
- limited structured evidence volume
Main caveats
- preclinical evidence outweighs human evidence
- limited central evidence
Internal review flags
1 flagsPrimary central evidence
3 papersSkin Microbiome Compositional Changes in Atopic Dermatitis Accompany Dead Sea Climatotherapy.
2019Photochemistry and photobiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Co-occurrence network analysis reveals the alterations of the skin microbiome and metabolome in adults with mild to moderate atopic dermatitis.
2024mSystems
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Mild atopic dermatitis is characterized by increase in non-staphylococcus pathobionts and loss of specific species.
2024Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Supporting primary evidence
1 papersStaphylococcus aureus and the microbial ecology of atopic dermatitis.
1977Canadian journal of microbiology
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
6 papersAssessment of a contact-plate sampling technique and subsequent quantitative bacterial studies in atopic dermatitis.
1990The British journal of dermatology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Isolation, biochemical characterization, and cloning of a bacteriocin from the poultry-associated Staphylococcus aureus strain CH-91.
2013Applied microbiology and biotechnology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Alterations of Epidermal Lipid Profiles and Skin Microbiome in Children With Atopic Dermatitis.
2023Allergy, asthma & immunology research
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Spectral characterization of a blue light-emitting micro-LED platform on skin-associated microbial chromophores.
2024Biomedical optics express
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Resilience of the Skin Microbiome in Atopic Dermatitis During Short-Term Topical Treatment.
2025International journal of molecular sciences
Disease-relevant preclinical or model-based paper useful as supporting evidence.
A skin isolate of Micrococcus luteus negates the Staphylococcus aureus-induced release of type 2 cytokines from keratinocytes.
2026Frontiers in immunology
Disease-relevant preclinical or model-based paper useful as supporting evidence.