no_central_evidence
No primary central evidence rows were classified for this signal-disease pair.
candidateweakhigh inflation risk
Evenness
atopic dermatitis
Evenness has meaningful literature visibility in atopic dermatitis, but the current evidence mix suggests a substantial risk of overclaiming.
Evenness has a broader but less central evidence footprint in atopic dermatitis, with support coming from indirect, review, or preclinical literature.
evenness
Credibility score
6
Human translation
1/5
Reproducibility
1/5
Novelty
5/5
Actionability
1/5
Credibility 6Human translation 1/5Reproducibility 1/5Novelty 5/5Actionability 1/5
Why this scores the way it does
- meaningful supporting human literature
Main caveats
- preclinical evidence outweighs human evidence
- limited central evidence
Internal review flags
2 flagspreclinical_heavy
Preclinical evidence exceeds central human evidence. Interpret translational relevance cautiously.
Supporting primary evidence
2 papersMicrobial community profiling shows dysbiosis in the lesional skin of Vitiligo subjects.
2016Scientific reports
Human primary paper with plausible association relevance to the disease context.
Multi-omics analyses reveal interactions between the skin microbiota and skin metabolites in atopic dermatitis.
2024Frontiers in microbiology
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
7 papersITS2 Sequencing and Targeted Meta-Proteomics of Infant Gut Mycobiome Reveal the Functional Role of Rhodotorula sp. during Atopic Dermatitis Manifestation.
2021Journal of fungi (Basel, Switzerland)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
The Skin and Nose Microbiome and Its Association with Filaggrin Gene Mutations in Pediatric Atopic Dermatitis.
2022Dermatology (Basel, Switzerland)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L descriptive systems and utilities in atopic dermatitis.
2023The European journal of health economics : HEPAC : health economics in prevention and care
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Exploring the Differences in the Gut Microbiome in Atopic Dermatitis According to the Presence of Gastrointestinal Symptoms.
2022Journal of clinical medicine
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Skin microbiome and its association with host cofactors in determining atopic dermatitis severity.
2023Journal of the European Academy of Dermatology and Venereology : JEADV
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Resilience of the Skin Microbiome in Atopic Dermatitis During Short-Term Topical Treatment.
2025International journal of molecular sciences
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Preliminary Characterization of Skin Microbiota and Mycobiota in Atopic Dermatitis by Metagenomic and Culture-Based Analyses.
2026Life (Basel, Switzerland)
Disease-relevant preclinical or model-based paper useful as supporting evidence.