Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified.
2013PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
fulltoplow inflation risk
Eubacterium hallii
autism
Eubacterium hallii is an interesting but still moderate-confidence signal in autism.
Eubacterium hallii shows a strong literature footprint in autism, with substantial central evidence and broader supporting literature.
eubacterium_hallii
Credibility score
46
Human translation
5/5
Reproducibility
4/5
Novelty
3/5
Actionability
4/5
Credibility 46Human translation 5/5Reproducibility 4/5Novelty 3/5Actionability 4/5
Why this scores the way it does
- strong central evidence base
Main caveats
- directionality and confounding still require curated review
Primary central evidence
16 papersAltered gut microbiota and short chain fatty acids in Chinese children with autism spectrum disorder.
2019Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[Correlation between gut microbiota and behavior symptoms in children with autism spectrum disorder].
2019Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The bacterial neurometabolic signature of the gut microbiota of young children with autism spectrum disorders.
2020Journal of medical microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota Dysbiosis Associated With Altered Production of Short Chain Fatty Acids in Children With Neurodevelopmental Disorders.
2020Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Probiotic and Oxytocin Combination Therapy in Patients with Autism Spectrum Disorder: A Randomized, Double-Blinded, Placebo-Controlled Pilot Trial.
2021Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Comparison of gut microbiota in autism spectrum disorders and neurotypical boys in China: A case-control study.
2021Synthetic and systems biotechnology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Correlation among gut microbiota, fecal metabolites and autism-like behavior in an adolescent valproic acid-induced rat autism model.
2022Behavioural brain research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal Microbiota Transplantation Relieves Gastrointestinal and Autism Symptoms by Improving the Gut Microbiota in an Open-Label Study.
2021Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Sex-specific differences in the gut microbiota and fecal metabolites in an adolescent valproic acid-induced rat autism model.
2021Frontiers in bioscience (Landmark edition)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Understanding the link between gut microbiota, dietary intake, and nutritional status in children with autism and typical development.
2023Frontiers in nutrition
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Altered Gut Microbiota and Short-chain Fatty Acids in Chinese Children with Constipated Autism Spectrum Disorder.
2023Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Alteration of the gut microbiota profile in children with autism spectrum disorder in China.
2023Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Metagenomic Characterization of Gut Microbiota in Children with Autism Spectrum Disorder: Microbial Signatures and Modulation by Anti-Inflammatory Diet and Probiotics.
2025Pharmaceuticals (Basel, Switzerland)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Bifidobacterium adolescentis DM8504 Alleviates Autistic-Like Behaviors in Valproic Acid-Exposed Rats Through Gut Microbiota Modulation and SCFA Restoration.
2025Neuropsychiatric disease and treatment
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Identifying gut microbiota composition disparities in autistic individuals and their unaffected siblings: correlations with clinical characteristics.
2025Translational psychiatry
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Supporting primary evidence
1 papersThe Difference of Gut Microbiota and Their Correlations With Urinary Organic Acids Between Autistic Children With and Without Atopic Dermatitis.
2022Frontiers in cellular and infection microbiology
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
4 papersRevealing the beneficial effects of a dairy infant formula on the gut microbiota of early childhood children with autistic spectrum disorder using static and SHIME® fermentation models.
2023Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Uncovering novel endocannabinoidome-gut microbiome-brain axis-based therapeutic targets in a Fragile X Syndrome mouse model.
2026Progress in neuro-psychopharmacology & biological psychiatry
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut microbiome composition and strain-sharing in multiplex autism spectrum disorder families.
2026Nature communications
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Microbial and metabolic profiles in autism spectrum disorder with atopic dermatitis in children.
2026AMB Express
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
4 papersBifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut.
2016Frontiers in microbiology
Relevant review or meta-analysis for the signal-disease area.
Overlapping Mechanisms of Action of Brain-Active Bacteria and Bacterial Metabolites in the Pathogenesis of Common Brain Diseases.
2022Nutrients
Relevant review or meta-analysis for the signal-disease area.
Gut microbiota dysbiosis at the interface of neuropsychiatric disorders and their dermatological comorbidities.
2025Gut microbes
Relevant review or meta-analysis for the signal-disease area.
Alterations in gut microbiota composition in neurodevelopmental disorders: a systematic review and meta-analysis.
2025Frontiers in microbiology
Relevant review or meta-analysis for the signal-disease area.