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Dialister

obesity

Dialister appears to be a strong and relatively human-grounded signal in obesity.

Dialister shows a strong literature footprint in obesity, with substantial central evidence and broader supporting literature.

dialister
Credibility score
90
Human translation
5/5
Reproducibility
5/5
Novelty
2/5
Actionability
5/5
Credibility 90Human translation 5/5Reproducibility 5/5Novelty 2/5Actionability 5/5
Why this scores the way it does
  • strong central evidence base
  • meaningful supporting human literature
Main caveats
  • directionality and confounding still require curated review

Primary central evidence

32 papers
Oral supplementation with L-glutamine alters gut microbiota of obese and overweight adults: A pilot study.
2015
Nutrition (Burbank, Los Angeles County, Calif.)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Body size phenotypes comprehensively assess cardiometabolic risk and refine the association between obesity and gut microbiota.
2018
International journal of obesity (2005)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota and Body Weight in School-Aged Children: The KOALA Birth Cohort Study.
2018
Obesity (Silver Spring, Md.)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Michigan cohorts to determine associations of maternal pre-pregnancy body mass index with pregnancy and infant gastrointestinal microbial communities: Late pregnancy and early infancy.
2019
PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria.
2019
Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Faecal Microbiota Are Related to Insulin Sensitivity and Secretion in Overweight or Obese Adults.
2019
Journal of clinical medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Ketonuria Is Associated with Changes to the Abundance of Roseburia in the Gut Microbiota of Overweight and Obese Women at 16 Weeks Gestation: A Cross-Sectional Observational Study.
2019
Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Alteration of the gut microbiota associated with childhood obesity by 16S rRNA gene sequencing.
2020
PeerJ
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Soy food intake associates with changes in the metabolome and reduced blood pressure in a gut microbiota dependent manner.
2020
Nutrition, metabolism, and cardiovascular diseases : NMCD
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Exercise training modulates the gut microbiota profile and impairs inflammatory signaling pathways in obese children.
2020
Experimental & molecular medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Baseline Oral Microbiome and All-cancer Incidence in a Cohort of Nonsmoking Mexican American Women.
2021
Cancer prevention research (Philadelphia, Pa.)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The role of the gut microbiota on the metabolic status of obese children.
2021
Microbial cell factories
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Comparison of gut microbiota between adults with autism spectrum disorder and obese adults.
2021
PeerJ
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The association between obesity and weight loss after bariatric surgery on the vaginal microbiota.
2021
Microbiome
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A predictive regression model of the obesity-related inflammatory status based on gut microbiota composition.
2021
International journal of obesity (2005)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy.
2021
Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota in pregnant Malaysian women: a comparison between trimesters, body mass index and gestational diabetes status.
2022
BMC pregnancy and childbirth
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats.
2022
Microbiology spectrum
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
An Investigation into the Correlation of Intestinal Flora with Obesity and Gestational Diabetes Mellitus.
2022
Computational and mathematical methods in medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The relationship of Megamonas species with nonalcoholic fatty liver disease in children and adolescents revealed by metagenomics of gut microbiota.
2022
Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Impact of Visceral Obesity on Structural and Functional Alterations of Gut Microbiota in Polycystic Ovary Syndrome (PCOS): A Pilot Study Using Metagenomic Analysis.
2023
Diabetes, metabolic syndrome and obesity : targets and therapy
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Adiposity is associated with expansion of the genus Dialister in rheumatoid arthritis patients.
2023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Virulence Factors of the Gut Microbiome Are Associated with BMI and Metabolic Blood Parameters in Children with Obesity.
2023
Microbiology spectrum
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of synbiotic supplementation on intestinal microbiota composition in children and adolescents with exogenous obesity: (Probesity-2 trial).
2023
Gut pathogens
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Analysis of 16s rRNA Gene Sequencing in Feces: The Impact of Bariatric Surgery on the Gut Microbiota in Patients with Obesity.
2024
Obesity surgery
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Dysbiotic alteration in the fecal microbiota of patients with polycystic ovary syndrome.
2024
Microbiology spectrum
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Diet and the Gut Microbiome as Determinants Modulating Metabolic Outcomes in Young Obese Adults.
2024
Biomedicines
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Individual Difference in the Capacity of Gut Microbiota to Ferment Four Complex Carbohydrates from Normal to Overweight People: An In Vitro Study.
2024
Journal of agricultural and food chemistry
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiome and Metabolome Alterations in Overweight or Obese Adult Population after Weight-Loss Bifidobacterium breve BBr60 Intervention: A Randomized Controlled Trial.
2024
International journal of molecular sciences
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut flora influences the hypothalamic-gonadal axis to regulate the pathogenesis of obesity-associated precocious puberty.
2024
Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Bariatric surgery promotes recruitment of brown fat linked to alterations in the gut microbiota.
2025
European journal of endocrinology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of beinaglutide on visceral fat area and gut microbiota in obesity.
2025
European journal of medical research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.

Supporting primary evidence

2 papers
Impact of salivary and pancreatic amylase gene copy numbers on diabetes, obesity, and functional profiles of microbiome in Northern Japanese population.
2022
Scientific reports
Human primary paper with plausible association relevance to the disease context.
Metabolomic profiles of obesity and subgingival microbiome in periodontally healthy individuals: A cross-sectional study.
2023
Journal of clinical periodontology
Human primary paper with plausible association relevance to the disease context.

Preclinical supporting evidence

5 papers
The gut microbiota of Colombians differs from that of Americans, Europeans and Asians.
2014
BMC microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent.
2021
Pathogens (Basel, Switzerland)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut Microbiome Alterations in Patients With Visceral Obesity Based on Quantitative Computed Tomography.
2021
Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals.
2022
BMC medicine
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut microbiome composition and metabolic activity in metabolic-associated fatty liver disease.
2025
Virulence
Disease-relevant preclinical or model-based paper useful as supporting evidence.

Review supporting evidence

6 papers
Gut Microbiome Composition in Obese and Non-Obese Persons: A Systematic Review and Meta-Analysis.
2021
Nutrients
Relevant review or meta-analysis for the signal-disease area.
Probiotics in the Prevention and Treatment of Gestational Diabetes Mellitus (GDM): A Review.
2022
Nutrients
Relevant review or meta-analysis for the signal-disease area.
The Gut Microbiome and Female Health.
2022
Biology
Relevant review or meta-analysis for the signal-disease area.
Does the ketogenic diet improve neurological disorders by influencing gut microbiota? A systematic review.
2023
Nutrition journal
Relevant review or meta-analysis for the signal-disease area.
The alteration of gut microbiota composition in patients with epilepsy: A systematic review and meta-analysis.
2025
Microbial pathogenesis
Relevant review or meta-analysis for the signal-disease area.
Precocious puberty and gut microbiome: a systematic review and meta-analysis.
2025
Pediatric research
Relevant review or meta-analysis for the signal-disease area.