The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy.
2019NPJ biofilms and microbiomes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
supportedmidmoderate inflation risk
Dialister
autism
Dialister is an interesting but still moderate-confidence signal in autism.
Dialister shows a moderate evidence base in autism, with multiple central papers and additional supporting literature.
dialister
Credibility score
19
Human translation
4/5
Reproducibility
2/5
Novelty
4/5
Actionability
2/5
Credibility 19Human translation 4/5Reproducibility 2/5Novelty 4/5Actionability 2/5
Why this scores the way it does
- moderate central evidence base
Main caveats
- directionality and confounding still require curated review
Primary central evidence
6 papersChanges in the Gut Microbiota of Children with Autism Spectrum Disorder.
2020Autism research : official journal of the International Society for Autism Research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Comparison of gut microbiota between adults with autism spectrum disorder and obese adults.
2021PeerJ
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Comparison of gut microbiota in autism spectrum disorders and neurotypical boys in China: A case-control study.
2021Synthetic and systems biotechnology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[Diversity and functional prediction of gut microbiota in children with autism spectrum disorder].
2022Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Omic characterizing and targeting gut dysbiosis in children with autism spectrum disorder: symptom alleviation through combined probiotic and medium-carbohydrate diet intervention - a pilot study.
2024Gut microbes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Preclinical supporting evidence
2 papersNew evidences on the altered gut microbiota in autism spectrum disorders.
2017Microbiome
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gastrointestinal, Behaviour and Anxiety Outcomes in Autistic Children Following an Open Label, Randomised Pilot Study of Synbiotics vs Synbiotics and Gut-Directed Hypnotherapy.
2026Journal of autism and developmental disorders
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
4 papersAltered composition and function of intestinal microbiota in autism spectrum disorders: a systematic review.
2019Translational psychiatry
Relevant review or meta-analysis for the signal-disease area.
An approach to gut microbiota profile in children with autism spectrum disorder.
2020Environmental microbiology reports
Relevant review or meta-analysis for the signal-disease area.
The Role of Gut Microbiota in Various Neurological and Psychiatric Disorders-An Evidence Mapping Based on Quantified Evidence.
2023Mediators of inflammation
Relevant review or meta-analysis for the signal-disease area.
Perturbations in gut microbiota in autism spectrum disorder: a systematic review.
2025Frontiers in neuroscience
Relevant review or meta-analysis for the signal-disease area.