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Desulfovibrio

type 2 diabetes

Desulfovibrio is an interesting but still moderate-confidence signal in type 2 diabetes.

Desulfovibrio shows a strong literature footprint in type 2 diabetes, with substantial central evidence and broader supporting literature.

desulfovibrio
Credibility score
59
Human translation
3/5
Reproducibility
4/5
Novelty
3/5
Actionability
5/5
Credibility 59Human translation 3/5Reproducibility 4/5Novelty 3/5Actionability 5/5
Why this scores the way it does
  • strong central evidence base
  • substantial preclinical support
Main caveats
  • directionality and confounding still require curated review

Internal review flags

1 flags
sparse_primary_supporting_bucket

Central evidence is high but primary supporting bucket is empty. Classification tiers may still be too coarse.

Primary central evidence

20 papers
Differential Changes in Gut Microbiota After Gastric Bypass and Sleeve Gastrectomy Bariatric Surgery Vary According to Diabetes Remission.
2017
Obesity surgery
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Role of Gut Microbiota on Cardio-Metabolic Parameters and Immunity in Coronary Artery Disease Patients with and without Type-2 Diabetes Mellitus.
2017
Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Inulin-type fructan improves diabetic phenotype and gut microbiota profiles in rats.
2018
PeerJ
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
2018
Microbiome
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Roles of 27 Genera of Human Gut Microbiota in Ischemic Heart Disease, Type 2 Diabetes Mellitus, and Their Risk Factors: A Mendelian Randomization Study.
2018
American journal of epidemiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal microbiota transplantation improves metabolism and gut microbiome composition in db/db mice.
2020
Acta pharmacologica Sinica
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans.
2020
Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Feruloylated oligosaccharides and ferulic acid alter gut microbiome to alleviate diabetic syndrome.
2020
Food research international (Ottawa, Ont.)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Health improvements of type 2 diabetic patients through diet and diet plus fecal microbiota transplantation.
2022
Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Habitual Dietary Fiber Intake, Fecal Microbiota, and Hemoglobin A1c Level in Chinese Patients with Type 2 Diabetes.
2022
Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Amelioration of type 2 diabetes by the novel 6, 8-guanidyl luteolin quinone-chromium coordination via biochemical mechanisms and gut microbiota interaction.
2023
Journal of advanced research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
High-fiber diet ameliorates gut microbiota, serum metabolism and emotional mood in type 2 diabetes patients.
2023
Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Penthorum chinense Pursh improves type 2 diabetes mellitus via modulating gut microbiota in db/db mice.
2023
BMC complementary medicine and therapies
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Synergism of Human Lactobacillaceae and Inulin Decrease Hyperglycemia via Regulating the Composition of Gut Microbiota and Metabolic Profiles in db/db Mice.
2023
Journal of microbiology and biotechnology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiome signatures associated with type 2 diabetes in obesity in Mongolia.
2024
Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut-kidney axis.
2024
Frontiers in pharmacology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut vs. vaginal microbiome in diabetes Progression: Key microbial shifts and implications.
2025
Microbial pathogenesis
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Modulatory Role of Hesperetin-Copper(II) on Gut Microbiota in Type 2 Diabetes Mellitus Mice.
2025
Foods (Basel, Switzerland)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Acylated Canna edulis starch improves type 2 diabetes in vitro and in vivo via gut microbiota-derived SCFA enrichment.
2025
International journal of biological macromolecules
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Liuwei Dihuang pills ameliorate renal injury in experimental type 2 diabetes mellitus rat by regulating host-gut microbiota interaction.
2025
Frontiers in pharmacology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.

Preclinical supporting evidence

19 papers
Hypoglycemic Mechanism of the Berberine Organic Acid Salt under the Synergistic Effect of Intestinal Flora and Oxidative Stress.
2018
Oxidative medicine and cellular longevity
Disease-relevant preclinical or model-based paper useful as supporting evidence.
JinQi Jiangtang Tablet Regulates Gut Microbiota and Improve Insulin Sensitivity in Type 2 Diabetes Mice.
2019
Journal of diabetes research
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Identifying psychiatric disorder-associated gut microbiota using microbiota-related gene set enrichment analysis.
2020
Briefings in bioinformatics
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Fermented carrot juice attenuates type 2 diabetes by mediating gut microbiota in rats.
2019
Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
A Purified Anthraquinone-Glycoside Preparation From Rhubarb Ameliorates Type 2 Diabetes Mellitus by Modulating the Gut Microbiota and Reducing Inflammation.
2019
Frontiers in microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Lactobacillus acidophilus alleviates type 2 diabetes by regulating hepatic glucose, lipid metabolism and gut microbiota in mice.
2019
Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Arabinoxylan ameliorates type 2 diabetes by regulating the gut microbiota and metabolites.
2022
Food chemistry
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Pi-Dan-Jian-Qing Decoction Ameliorates Type 2 Diabetes Mellitus Through Regulating the Gut Microbiota and Serum Metabolism.
2021
Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Effects of Auricularia auricula Polysaccharides on Gut Microbiota Composition in Type 2 Diabetic Mice.
2022
Molecules (Basel, Switzerland)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Analysis of subgingival micro-organisms based on multi-omics and Treg/Th17 balance in type 2 diabetes with/without periodontitis.
2022
Frontiers in microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Ethanol extract of propolis regulates type 2 diabetes in mice via metabolism and gut microbiota.
2023
Journal of ethnopharmacology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Low glycemic index potato biscuits alleviate physio-histological damage and gut dysbiosis in rats with type-2 diabetes mellitus induced by high-sugar and high-fat diet and streptozotocin.
2023
The Journal of nutritional biochemistry
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Fagopyrum tataricum ethanol extract ameliorates symptoms of hyperglycemia by regulating gut microbiota in type 2 diabetes mellitus mice.
2023
Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Effects of Bifidobacterium BL21 and Lacticaseibacillus LRa05 on gut microbiota in type 2 diabetes mellitus mice.
2023
AMB Express
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Integrated 16S rRNA sequencing and nontargeted metabolomics analysis to reveal the mechanisms of Yu-Ye Tang on type 2 diabetes mellitus rats.
2023
Frontiers in endocrinology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Phage cocktail alleviated type 2 diabetes by reshaping gut microbiota and decreasing proinflammatory cytokines.
2024
Applied microbiology and biotechnology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Alleviating effects of polyphenol extract from rapeseed meal on type 2 diabetes in mice via modulation of gut microbiota and AMPK/mTOR signaling pathways.
2025
Food research international (Ottawa, Ont.)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Mechanistic analysis of Inonotus hispidus in ameliorating T2DM: Metabolomics and gut microbiota profiling in mice models.
2025
Fitoterapia
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gentiopicroside alleviates type 2 diabetes mellitus by attenuating oxidative stress and reshaping gut microbiota in high-fat diet and streptozotocin-induced mice.
2026
Frontiers in nutrition
Disease-relevant preclinical or model-based paper useful as supporting evidence.

Review supporting evidence

1 papers
Relationship between changes in microbiota induced by resveratrol and its anti-diabetic effect on type 2 diabetes.
2022
Frontiers in nutrition
Relevant review or meta-analysis for the signal-disease area.