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Coprococcus

type 2 diabetes

Coprococcus is an interesting but still moderate-confidence signal in type 2 diabetes.

Coprococcus shows a strong literature footprint in type 2 diabetes, with substantial central evidence and broader supporting literature.

coprococcus
Credibility score
53
Human translation
4/5
Reproducibility
4/5
Novelty
3/5
Actionability
3/5
Credibility 53Human translation 4/5Reproducibility 4/5Novelty 3/5Actionability 3/5
Why this scores the way it does
  • strong central evidence base
Main caveats
  • directionality and confounding still require curated review

Primary central evidence

19 papers
Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters.
2013
The pharmacogenomics journal
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Relationship between gut microbiota and type 2 diabetic erectile dysfunction in Sprague-Dawley rats.
2017
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Faecal Microbiota Are Related to Insulin Sensitivity and Secretion in Overweight or Obese Adults.
2019
Journal of clinical medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity.
2019
Gut microbes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Associations between habitual diet, metabolic disease, and the gut microbiota using latent Dirichlet allocation.
2021
Microbiome
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Starch acylation of different short-chain fatty acids and its corresponding influence on gut microbiome and diabetic indexes.
2022
Food chemistry
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota mediate melatonin signalling in association with type 2 diabetes.
2022
Diabetologia
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).
2022
Diabetes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of Smoking on the Gut Microbiota in Individuals with Type 2 Diabetes Mellitus.
2022
Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota and Serum Metabolites in Individuals with Class III Obesity Without Type 2 Diabetes Mellitus: Pilot Analysis.
2023
Metabolic syndrome and related disorders
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Compositional alterations of the gut microbiota in acute myocardial infarction patients with type 2 diabetes mellitus.
2023
Annals of translational medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Enhanced trimethylamine metabolism and gut dysbiosis in type 2 diabetes mellitus with microalbumin.
2023
Frontiers in endocrinology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Differences in gut microbiota between Dutch and South-Asian Surinamese: potential implications for type 2 diabetes mellitus.
2024
Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota in Patients with Prediabetes.
2024
Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
ZiBu PiYin recipe regulates central and peripheral Aβ metabolism and improves diabetes-associated cognitive decline in ZDF rats.
2025
Journal of ethnopharmacology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fava bean and buckwheat are sustainable food sources which support satiety and beneficially modulate several biomarkers, bacteria and metabolites associated with human health.
2025
European journal of nutrition
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Fecal microbiome analysis in patients with metabolic syndrome and type 2 diabetes.
2025
PeerJ
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Comparison of the Gut Microbiome Composition, Serum Inflammatory Markers and Faecal Short-Chain Fatty Acids Among Individuals With Type 1 and 2 Diabetes Mellitus With Healthy Controls: A Case-Control Study.
2025
Endocrinology, diabetes & metabolism
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A species of Coprococcus is related to BMI in patients who underwent malabsorptive bariatric surgery and its abundance is modified by magnesium and thiamin intake.
2025
Frontiers in endocrinology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.

Preclinical supporting evidence

7 papers
Effect of heat-killed Streptococcus thermophilus on type 2 diabetes rats.
2019
PeerJ
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Black bean husk and black rice anthocyanin extracts modulated gut microbiota and serum metabolites for improvement in type 2 diabetic rats.
2022
Food & function
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Simiao Wan modulates the gut microbiota and bile acid metabolism during improving type 2 diabetes mellitus in mice.
2022
Phytomedicine : international journal of phytotherapy and phytopharmacology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Integrating Choline and Specific Intestinal Microbiota to Classify Type 2 Diabetes in Adults: A Machine Learning Based Metagenomics Study.
2022
Frontiers in endocrinology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
A Chinese medical nutrition therapy diet accompanied by intermittent energy restriction alleviates type 2 diabetes by enhancing pancreatic islet function and regulating gut microbiota composition.
2022
Food research international (Ottawa, Ont.)
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Hypoglycemic and intestinal microbiota-regulating effects of melanoidins in diabetic mice.
2025
Journal of the science of food and agriculture
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Anaerobutyricum soehngenii improves glycemic control and other markers of cardio-metabolic health in adults at risk of type 2 diabetes.
2025
Gut microbes
Disease-relevant preclinical or model-based paper useful as supporting evidence.

Review supporting evidence

3 papers
Modulation of the gut microbiome: a systematic review of the effect of bariatric surgery.
2018
European journal of endocrinology
Relevant review or meta-analysis for the signal-disease area.
Gut Microbiota in Patients with Polycystic Ovary Syndrome: a Systematic Review.
2022
Reproductive sciences (Thousand Oaks, Calif.)
Relevant review or meta-analysis for the signal-disease area.
Diet and the gut microbiota profiles in individuals at risk of chronic heart failure - A review on the Asian population.
2025
Asia Pacific journal of clinical nutrition
Relevant review or meta-analysis for the signal-disease area.