Reduced incidence of Prevotella and other fermenters in intestinal microflora of autistic children.
2013PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
supportedmidmoderate inflation risk
Coprococcus
autism
Coprococcus is an interesting but still moderate-confidence signal in autism.
Coprococcus shows a moderate evidence base in autism, with multiple central papers and additional supporting literature.
coprococcus
Credibility score
31
Human translation
5/5
Reproducibility
3/5
Novelty
3/5
Actionability
3/5
Credibility 31Human translation 5/5Reproducibility 3/5Novelty 3/5Actionability 3/5
Why this scores the way it does
- moderate central evidence base
Main caveats
- directionality and confounding still require curated review
Primary central evidence
10 papersTreatment with the traditional Chinese medicine BuYang HuanWu Tang induces alterations that normalize the microbiome in ASD patients.
2020Bioscience of microbiota, food and health
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Maternal Immune Activation Causes Social Behavior Deficits and Hypomyelination in Male Rat Offspring with an Autism-Like Microbiota Profile.
2021Brain sciences
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Changes in the stool and oropharyngeal microbiome in obsessive-compulsive disorder.
2022Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Altered Gut Microbiota as Potential Biomarkers for Autism Spectrum Disorder in Early Childhood.
2023Neuroscience
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Infant microbes and metabolites point to childhood neurodevelopmental disorders.
2024Cell
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Stratification of Gut Microbiota Profiling Based on Autism Neuropsychological Assessments.
2024Microorganisms
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Metagenomic Characterization of Gut Microbiota in Children with Autism Spectrum Disorder: Microbial Signatures and Modulation by Anti-Inflammatory Diet and Probiotics.
2025Pharmaceuticals (Basel, Switzerland)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A novel synbiotic (SCM06) for anxiety and sensory hyperresponsiveness in children with autism spectrum disorder: an open-label pilot study.
2026NPJ biofilms and microbiomes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota and its association with gastrointestinal symptoms and pharmacological treatments in a sibling-matched cohort with autism spectrum disorder.
2026Frontiers in microbiomes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Preclinical supporting evidence
2 papersAnalysis of gut microbiome, nutrition and immune status in autism spectrum disorder: a case-control study in Ecuador.
2020Gut microbes
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Multi-omics analyses demonstrate the modulating role of gut microbiota on the associations of unbalanced dietary intake with gastrointestinal symptoms in children with autism spectrum disorder.
2023Gut microbes
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
7 papersAn approach to gut microbiota profile in children with autism spectrum disorder.
2020Environmental microbiology reports
Relevant review or meta-analysis for the signal-disease area.
Composition of Gut Microbiota in Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.
2020Nutrients
Relevant review or meta-analysis for the signal-disease area.
Overlapping Mechanisms of Action of Brain-Active Bacteria and Bacterial Metabolites in the Pathogenesis of Common Brain Diseases.
2022Nutrients
Relevant review or meta-analysis for the signal-disease area.
Gut Microbiota Profiles in Children and Adolescents with Psychiatric Disorders.
2022Microorganisms
Relevant review or meta-analysis for the signal-disease area.
The Role of Gut Microbiota in Various Neurological and Psychiatric Disorders-An Evidence Mapping Based on Quantified Evidence.
2023Mediators of inflammation
Relevant review or meta-analysis for the signal-disease area.
Genus-Level Analysis of Gut Microbiota in Children with Autism Spectrum Disorder: A Mini Review.
2023Children (Basel, Switzerland)
Relevant review or meta-analysis for the signal-disease area.
Perturbations in gut microbiota in autism spectrum disorder: a systematic review.
2025Frontiers in neuroscience
Relevant review or meta-analysis for the signal-disease area.