Dominant and diet-responsive groups of bacteria within the human colonic microbiota.
2011The ISME journal
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
fulltoplow inflation risk
Collinsella aerofaciens
obesity
Collinsella aerofaciens appears to be a strong and relatively human-grounded signal in obesity.
Collinsella aerofaciens shows a strong literature footprint in obesity, with substantial central evidence and broader supporting literature.
collinsella_aerofaciens
Credibility score
85
Human translation
5/5
Reproducibility
5/5
Novelty
2/5
Actionability
5/5
Credibility 85Human translation 5/5Reproducibility 5/5Novelty 2/5Actionability 5/5
Why this scores the way it does
- strong central evidence base
- meaningful supporting human literature
Main caveats
- directionality and confounding still require curated review
Primary central evidence
30 papersConnections Between the Gut Microbiome and Metabolic Hormones in Early Pregnancy in Overweight and Obese Women.
2016Diabetes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Low dietary fiber intake increases Collinsella abundance in the gut microbiota of overweight and obese pregnant women.
2018Gut microbes
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Sex Differences in the Gut Microbiota as Potential Determinants of Gender Predisposition to Disease.
2019Molecular nutrition & food research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study.
2019PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Metatranscriptomic analysis to define the Secrebiome, and 16S rRNA profiling of the gut microbiome in obesity and metabolic syndrome of Mexican children.
2020Microbial cell factories
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Low-carbohydrate high-fat weight reduction diet induces changes in human gut microbiota.
2021MicrobiologyOpen
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiota Profile and Its Association with Clinical Variables and Dietary Intake in Overweight/Obese and Lean Subjects: A Cross-Sectional Study.
2021Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
In Vitro Fecal Fermentation Patterns of Arabinoxylan from Rice Bran on Fecal Microbiota from Normal-Weight and Overweight/Obese Subjects.
2021Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Taxonomic Characterization and Short-Chain Fatty Acids Production of the Obese Microbiota.
2021Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
A predictive regression model of the obesity-related inflammatory status based on gut microbiota composition.
2021International journal of obesity (2005)
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy.
2021Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior.
2021Translational psychiatry
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The gut microbiota of non-obese Japanese pregnant women with gestational diabetes mellitus.
2022Bioscience of microbiota, food and health
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Association Between Fecal Short-Chain Fatty Acids, Gut Microbiota, and Visceral Fat in Monozygotic Twin Pairs.
2022Diabetes, metabolic syndrome and obesity : targets and therapy
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[Association between obesity with the diversity and genus of gut microbiota in school-aged children].
2022Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Beneficial Effects of a Low-Glycemic Diet on Serum Metabolites and Gut Microbiota in Obese Women With Prevotella and Bacteriodes Enterotypes: A Randomized Clinical Trial.
2022Frontiers in nutrition
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Impact of Fecal Microbiota Transplantation on Gut Bacterial Bile Acid Metabolism in Humans.
2022Nutrients
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Physical activity-induced alterations of the gut microbiota are BMI dependent.
2023FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Heptamethoxyflavone Alleviates Metabolic Syndrome in High-Fat Diet-Fed Mice by Regulating the Composition, Function, and Metabolism of Gut Microbiota.
2023Journal of agricultural and food chemistry
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of synbiotic supplementation on intestinal microbiota composition in children and adolescents with exogenous obesity: (Probesity-2 trial).
2023Gut pathogens
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Collinsella aerofaciens linked with increased ethanol production and liver inflammation contribute to the pathophysiology of NAFLD.
2024iScience
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Physical activity shifts gut microbiota structure in aged subjects with overweight/obesity and metabolic syndrome.
2024Biology of sport
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Diet and the Gut Microbiome as Determinants Modulating Metabolic Outcomes in Young Obese Adults.
2024Biomedicines
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Multi-omics insights into the microbiota-gut-brain axis and cognitive improvement post-bariatric surgery.
2024Journal of translational medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut flora influences the hypothalamic-gonadal axis to regulate the pathogenesis of obesity-associated precocious puberty.
2024Scientific reports
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gestational diabetes-combined excess weight gain exacerbates gut microbiota dysbiosis in newborns, associated with reduced abundance of Clostridium, Coriobacteriaceae, and Collinsella.
2024Frontiers in cellular and infection microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut Microbiome and Symptom Burden in Obese and Non-Obese Women Receiving Chemotherapy for Breast Cancer.
2025Biological research for nursing
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Effects of children's microbiota on adipose and intestinal development in sex-matched mice persist into adulthood following a single fecal microbiota transplantation.
2025Molecular metabolism
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Characterization of the gut microbiota in people with different levels of obesity.
2025Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Supporting primary evidence
2 papersGut Microbiota and Endothelial Dysfunction Markers in Obese Mexican Children and Adolescents.
2018Nutrients
Human primary paper with plausible association relevance to the disease context.
Early life gut microbiota is associated with rapid infant growth in Hispanics from Southern California.
2021Gut microbes
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
7 papersThe influence of whole grain products and red meat on intestinal microbiota composition in normal weight adults: a randomized crossover intervention trial.
2014PloS one
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associated with biopsy-proven nonalcoholic steatohepatitis.
2020Gut microbes
Disease-relevant preclinical or model-based paper useful as supporting evidence.
The Associations between Diet and Socioeconomic Disparities and the Intestinal Microbiome in Preadolescence.
2021Nutrients
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Gut Microbiota and Fear Processing in Women Affected by Obesity: An Exploratory Pilot Study.
2022Nutrients
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Intestinal microbiome characterization of adult Brazilian men with psoriasis compared to omnivore and vegetarian controls.
2023Anais brasileiros de dermatologia
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Exploring the relationship between the gut microbiota and cognitive function in schizophrenia patients with distinct weights.
2025Schizophrenia research
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Multi-omics analyses revealed the distinct effects of calorie restriction diets with different fat-to-energy ratios on body weight and glycolipid metabolism in rats.
2025The Journal of nutritional biochemistry
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
5 papersThe Modulation of Gut Microbiota Composition in the Pathophysiology of Gestational Diabetes Mellitus: A Systematic Review.
2021Biology
Relevant review or meta-analysis for the signal-disease area.
Characteristics of the Gut Bacterial Composition in People of Different Nationalities and Religions.
2022Microorganisms
Relevant review or meta-analysis for the signal-disease area.
Unraveling the gut microbiota's role in obesity: key metabolites, microbial species, and therapeutic insights.
2025Journal of bacteriology
Relevant review or meta-analysis for the signal-disease area.
Taxonomic and functional characteristics of the gut microbiota in obesity: A systematic review.
2025Endocrinologia, diabetes y nutricion
Relevant review or meta-analysis for the signal-disease area.
Impact of maternal diet on microbiota and health during pregnancy: a systematic review and correlational meta-analysis.
2026The American journal of clinical nutrition
Relevant review or meta-analysis for the signal-disease area.