Robust Microbial Markers for Non-Invasive Inflammatory Bowel Disease Identification.
2019IEEE/ACM transactions on computational biology and bioinformatics
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
supportedmidmoderate inflation risk
Anaerostipes hadrus
inflammatory bowel disease
Anaerostipes hadrus is an interesting but still moderate-confidence signal in inflammatory bowel disease.
Anaerostipes hadrus shows a moderate evidence base in inflammatory bowel disease, with multiple central papers and additional supporting literature.
anaerostipes_hadrus
Credibility score
39
Human translation
4/5
Reproducibility
3/5
Novelty
3/5
Actionability
3/5
Credibility 39Human translation 4/5Reproducibility 3/5Novelty 3/5Actionability 3/5
Why this scores the way it does
- moderate central evidence base
Main caveats
- directionality and confounding still require curated review
Primary central evidence
13 papersFecal and Mucosal Microbiota Profiling in Irritable Bowel Syndrome and Inflammatory Bowel Disease.
2019Frontiers in microbiology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
[Correlation between Vitamin D Status and Gut Microbiota in Patients with Inflammatory Bowel Disease].
2020Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Attributes of intestinal microbiota composition and their correlation with clinical primary non-response to anti-TNF-α agents in inflammatory bowel disease patients.
2022Bosnian journal of basic medical sciences
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Distinct alterations of fecal microbiota refer to the efficacy of adalimumab in Crohn's disease.
2022Frontiers in pharmacology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Microbial Disruptions in Inflammatory Bowel Disease: A Comparative Analysis.
2024International journal of general medicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
After Surgically Induced Remission, Ileal and Colonic Mucosa-Associated Microbiota Predicts Crohn's Disease Recurrence.
2025Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Gut microbiota diversity repeatedly diminishes over time following maintenance infliximab infusions in paediatric IBD patients.
2024PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Evaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota research.
2025EBioMedicine
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
The Fecal Microbiome of IBD Patients Is Less Divertible by Bowel Preparation Compared to Healthy Controls: Results From a Prospective Study.
2025Inflammatory bowel diseases
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
New potential biomarkers of ulcerative colitis and disease course - integrated metagenomic and metabolomic analysis among Polish patients.
2025Journal of gastroenterology
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Predicting Risk of Post-Treatment Relapse in Patients with Inflammatory Bowel Disease Based on Intestinal Microbiota.
2025Journal of inflammation research
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Colorectal adenoma presence is associated with decreased menaquinone pathway functions in the gut microbiome of patients undergoing routine colonoscopy.
2026PloS one
Direct disease-relevant human paper with strong clinical, biomarker, or mechanistic framing.
Supporting primary evidence
1 papersGut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field.
2023Microorganisms
Human primary paper with plausible association relevance to the disease context.
Preclinical supporting evidence
5 papersPrebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis.
2021Cellular and molecular gastroenterology and hepatology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Exploring the intestinal ecosystem: from gut microbiota to associations with subtypes of inflammatory bowel disease.
2023Frontiers in cellular and infection microbiology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Anaerostipes hadrus, a butyrate-producing bacterium capable of metabolizing 5-fluorouracil.
2024mSphere
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Rewiring Tryptophan Metabolism via Programmable Probiotic Integrated by Dual-Layered Microcapsule Protects against Inflammatory Bowel Disease in Mice.
2024ACS nano
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Cedrol ameliorates inflammatory bowel disease via mitochondrial biogenesis, gut microbiota restoration, and intestinal barrier repair.
2025Frontiers in pharmacology
Disease-relevant preclinical or model-based paper useful as supporting evidence.
Review supporting evidence
4 papersBifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut.
2016Frontiers in microbiology
Relevant review or meta-analysis for the signal-disease area.
Gut Microbiota Profile in Pediatric Patients With Inflammatory Bowel Disease: A Systematic Review.
2021Frontiers in pediatrics
Relevant review or meta-analysis for the signal-disease area.
Gut microbiota mediated T cells regulation and autoimmune diseases.
2024Frontiers in microbiology
Relevant review or meta-analysis for the signal-disease area.
Comparative analysis of Parkinson's and inflammatory bowel disease gut microbiomes reveals shared butyrate-producing bacteria depletion.
2025NPJ Parkinson's disease
Relevant review or meta-analysis for the signal-disease area.